Mental health outcomes of adults born very preterm or with very low birth weight

A systematic review

authored by
Rachel Robinson, Marius Lahti-Pulkkinen, Daniel Schnitzlein, Falk Voit, Polina Girchenko, Dieter Wolke, Sakari Lemola, Eero Kajantie, Kati Heinonen, Katri Räikkönen
Abstract

Preterm birth research is poised to explore the mental health of adults born very preterm(VP; <32+0 weeks gestational age) and/or very low birth weight(VLBW; <1500g) through individual participant data meta-analyses, but first the previous evidence needs to be understood. We systematically reviewed and assessed the quality of the evidence from VP/VLBW studies with mental health symptoms or disorders appearing in adulthood, excluding childhood onset disorders. Participants (≥18 years, born >1970) included VP/VLBW individuals with controls born at term(≥37+0 weeks) or with normal birth weight(NBW; ≥2500g). Thirteen studies were included. Studies consistently showed an increased risk for psychotropic medication use for VP/VLBW adults in comparison to NBW/term controls, but whether VP/VLBW adults have an increased risk for mental health disorders or symptoms appearing in adulthood remains uncertain. The quality of the evidence was moderate (65.8%) to high (34.2%). Further research in larger samples is needed.

Organisation(s)
Institute of Labour Economics
External Organisation(s)
University of Helsinki
German Institute for Economic Research (DIW)
Institute of Labor Economics (IZA)
University of Warwick
Bielefeld University
University of Oulu
Norwegian University of Science and Technology (NTNU)
University of Edinburgh
Finnish Institute for Health and Welfare (THL)
Type
Review article
Journal
Seminars in Fetal and Neonatal Medicine
Volume
25
ISSN
1744-165X
Publication date
06.2020
Publication status
Published
Peer reviewed
Yes
ASJC Scopus subject areas
Pediatrics, Perinatology, and Child Health
Sustainable Development Goals
SDG 3 - Good Health and Well-being
Electronic version(s)
http://urn.fi/urn:nbn:fi-fe2020092475667 (Access: Open)
http://wrap.warwick.ac.uk/136430/1/WRAP-mental-health-outcomes-adults-born-very-preterm-Wolke-2020.pdf (Access: Open)
https://doi.org/10.1016/j.siny.2020.101113 (Access: Closed)