Synthesis of odorants in flow and their applications in perfumery

authored by

Merlin Kleoff, Paul Kiler, Philipp Heretsch

Abstract

Continuous flow technology is a key technology for sustainable manufacturing with numerous applications for the synthesis of fine chemicals. In recent years, the preparation of odorants utilizing the advantages of flow reactors received growing attention. In this review, we give an overview of selected methods for the synthesis of odorants in flow, including heterogeneously catalyzed reactions, gas reactions, and photochemical C–H functionalization processes. After a brief introduction on types of odorants, the presented odorant syntheses are ordered according to the main odor families “fruity”, “green”, “marine”, “floral”, “spicy”, “woody”, “ambery”, and “musky” and their use and importance for perfumery is briefly discussed.

Organisation(s)

Institute of Organic Chemistry

External Organisation(s)

Freie Universität Berlin (FU Berlin)
PK Perfumes

Type

Review article

Journal

Beilstein Journal of Organic Chemistry

Volume

18

Pages

754-768

No. of pages

15

ISSN

1860-5397

Publication date

2022

Publication status

Published

Peer reviewed

Yes

ASJC Scopus subject areas

Organic Chemistry

Sustainable Development Goals

SDG 9 - Industry, Innovation, and Infrastructure, SDG 14 - Life Below Water

Electronic version(s)

https://doi.org/10.3762/bjoc.18.76 (Access: Open)