Sicherheit von Folsäure. Fakten und Fiktionen

authored by

A. Ströhle, Maike Wolters, A.  Hahn

Abstract

Improving dietary folate intake is a central public health goal. However, critical voices have become louder warning of too high intake of folic acid. Safety concerns of a high folic acid exposure are usually limited to synthetic folic acid contained in drugs and food supplements. Against this background, the present article focuses on two matters: (a) How do the absorption and metabolism of synthetic folic acid differ from that of other folates? (b) How has the longterm safety of folic acid to be judged, especially regarding the risk of colorectal cancer, autism, asthma, impaired immune defence, masking vitamin B12 deficiency and interactions with the methotrexate metabolism?.

Organisation(s)

Institute of Food Science and Human Nutrition
Nutrition Physiology and Human Nutrition Section

Type

Article

Journal

Medizinische Monatsschrift fur Pharmazeuten

Volume

38

Pages

297-306

No. of pages

10

ISSN

0342-9601

Publication date

01.08.2015

Publication status

Published

ASJC Scopus subject areas

Pharmacology (medical)

Sustainable Development Goals

SDG 3 - Good Health and Well-being