Optical properties of the human round window membrane

verfasst von

Martin Höhl, Daphne Detemple, Stefan Lyutenski, Georg Leuteritz, Arthur Varkentin, Heike Andrea Schmitt, Thomas Lenarz, Bernhard Roth, Merve Meinhardt-Wollweber, Uwe Morgner

Abstract

Optical techniques are effective tools for diagnostic applications in medicine and are particularly attractive for the noninvasive analysis of biological tissues and fluids in vivo. Noninvasive examinations of substances via a fiber optic probe need to consider the optical properties of biological tissues obstructing the optical path. This applies to the analysis of the human perilymph, which is located behind the round window membrane. The composition of this inner ear liquid is directly correlated to inner ear hearing loss. In this work, experimental methods for studying the optical properties of the human round window membrane ex vivo are presented. For the first time, a comprehensive investigation of this tissue is performed, including optical transmission, forward scattering, and Raman scattering. The results obtained suggest the application of visible wavelengths (>400nm) for investigating the perilymph behind the round window membrane in future.

Organisationseinheit(en)

Institut für Quantenoptik
Hannoversches Zentrum für Optische Technologien (HOT)

Externe Organisation(en)

Medizinische Hochschule Hannover (MHH)
Exzellenzcluster Hearing4all

Typ

Artikel

Journal

Journal of biomedical optics

Band

22

ISSN

1083-3668

Publikationsdatum

01.10.2017

Publikationsstatus

Veröffentlicht

Peer-reviewed

Ja

ASJC Scopus Sachgebiete

Elektronische, optische und magnetische Materialien, Biomaterialien, Atom- und Molekularphysik sowie Optik, Biomedizintechnik

Ziele für nachhaltige Entwicklung

SDG 3 – Gute Gesundheit und Wohlergehen

Elektronische Version(en)

https://doi.org/10.1117/1.JBO.22.10.105007 (Zugang: Offen)